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About us

Neuropeutics is a pharmaceutical company developing targeted therapies to extend neurodegenerative disease patients’ survival and improve their quality of life. One shared pathology across the wide range of neurodegenerative diseases (e.g., Alzheimer’s disease, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)) is TDP-43 pathology, which is associated with causing neurotoxicity and neuronal loss.

At Neuropeutics, we have had great success in developing novel high-throughput in vitro and in vivo models of TDP-43 pathology. Using these models, we identified an effective small molecule “JRMS-22” reducing pathology by 30% after two weeks of treatment in a mouse model. Based on our mechanistic understanding of disease, we have developed a novel approach to modulate, prevent, and reverse TDP-43 aggregation. Currently, our team is working relentlessly to finish IND enabling studies in preparation for clinical testing in those living ALS as our initial beachhead market.

Program engagement

Neuropeutics Inc

Leadership

Marc Shenouda

Co-Founder & CEO

Janice Robertson

Co-Founder and CSO

Status

Intellectual Property

Fundraising

Sector

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The Big DiF Innovation Factory's 15th Annual Open House on May 1 2025 from 4pm - 8pm

Join Innovation Factory's Annual Open House - The Big DiF!

Network with 300+ industry professionals, discover emerging solutions from our innovators, and celebrate entrepreneurship within the Hamilton-Halton ecosystem.

May 1, 2025 | 4:00pm – 8:00pm | Hamilton, Ontario